The analytical quality assurance of coagulation testing is complicated by the risk of applying non-commutable control materials and analytical drift related to reagent lot changes. Received: 10 March 2020 Accepted: 09 September 2020 Published: 30 October 2020. Keywords: Moving average quality assurance patient based real-time QC international normalized ratio (INR) activated partial thromboplastin time (aPTT) Furthermore, an otherwise undetected aPTT shift was detectable using MA QC. Finally, MA QC procedures were obtained that enabled detection of a ≥15% systematic error within a median of 27 test results (range 1–88 results) for INR and 22 test results (range 1–67 results) for aPTT.Ĭonclusions: MA QC procedures were obtained for INR and aPTT with relevant systematic error detection performance. Furthermore, when using the mean calculation for both INR and aPTT, truncation of higher results was required to enable detection of relevant error.
#Glims mips verification#
For aPTT when studying MA QC, a 2 second shift in aPTT results was noticed, which was not or not in the same amount detected by standard internal QC measurement and a aPTT verification procedure consisting of a 20 sample comparison study respectively. Results: Several MA QC procedures with various truncation limits and batch sizes were studied to select optimal MA QC.
#Glims mips software#
Optimization focused only on the mean calculation since only this calculation algorithm was supported by the laboratory software used to operate MA QC. Optimal MA QC was selected based on the overall systematic error detection properties.
#Glims mips generator#
The online MA Generator application ( was used to enable MA QC visualization, optimization and validation. Methods: Six months of historical INR and aPTT results were used as training dataset.
For all these reasons we aimed to optimize and validate moving average quality control (MA QC) procedures for the international normalized ratio (INR) and the activated partial thromboplastin time (aPTT) to enable real-time continuous quality control for these tests. Furthermore inherent to the practice of quality control measurements is its scheduled character. Please tick if you'd like to be placed on the mailing list to receive CliniSys related content e.g.Background: The analytical quality assurance of coagulation testing is complicated by the risk of applying non-commutable control materials and analytical drift related to reagent lot changes. Please tick to confirm that you have read and understood the CliniSys Privacy Policy
I do not yet have an account, but would like to request one First name:ĬliniSys product(s) you are responsible for: The support website also allows you to change your password at any given time using the menu function “My account -> Change password”. When your password has expired, you will be asked to choose a new password before you can login. MIPS services are guaranteed in times of Corona crisis.įor security reasons, the validity of your password for the MIPS support website will be limited to 365 days. The CliniSys support website is dedicated to our customers and allows downloading product service packs, consulting online documentation, registering support calls etc.
0 kommentar(er)
